What makes our technology unique?
RADIO FREQUENCY ENERGY (ulRFE) SPECTRUM
Magnetic fields are a fundamental part of life. They play a role in bird migration and fish navigation, among other phenomena. The earth’s magnetic field enables navigating with a compass. Magnetic fields exist whenever there is electric current; electricity provides a convenient means for creating magnetic fields for other uses, for example, in medicine. Magnetic fields have been used for various medical purposes since at least 2500 BC. Animals and bacteria sense the earth’s magnetic field. The search for how magnetic fields produce biological effects has driven exploration in a multitude of experimental systems, clinical studies, and the clinical use of FDA-approved devices. Various aspects of the effects of applied magnetic fields are understood, while others remain the subject of research. Even so, magnetic fields are used successfully for many medical applications, e.g., magnetic resonance imaging, to speed bone fracture repair, to increase the rate of wound healing, to decrease pain and to treat depression and obsessive-compulsive disorder. Today, there are numerous innovations involving magnetic fields that hold promise in a variety of life science applications.
Magnetic Fields
Magnetic fields arise from ferromagnetic materials, such as iron and nickel, or from electric current. For example, the earth’s magnetic field is generated by the molten iron alloy in the outer core. Medical applications take advantage of the interconnection between electricity and magnetic fields. Current in a wire produces a magnetic field. The properties of the field depend on the properties of the current. If the current’s amplitude does not change, it produces what is referred to as a static magnetic field. A current with changing amplitude produces an oscillating magnetic field. Both types of field have played a role in the biological investigations of magnetic field effects.
ulRFE®
EMulate Therapeutics, Inc. has developed a patented (40+ issued patents to date), proprietary technology using ulRFE® to produce therapeutic biological effects that have been demonstrated in plants, animals and now in humans. EMulate’s ulRFE technology produces a broadband, multifrequency oscillating magnetic field, with frequencies from 0 kHz up to roughly 22 kHz, that is obtained from recordings of selected molecules derived using its proprietary Magnetic Interrogation Device System or “MIDS.” While the details of the mechanism of action are not fully understood, recordings are hypothesized to capture noncovalent features of the recorded molecule that alter cellular behavior. EMulate’s ulRFE technology is currently in clinical testing for adults and children with terminal brain cancer, using an oscillating magnetic field created by its ulRFE technology, derived from the molecule paclitaxel. The technology is also in preclinical testing and in initial human testing, using oscillating magnetic fields derived from other specific molecules, for use in patients suffering from chronic or acute pain and from central nervous system disorders.
